Life Extension Optimized Folate L-Methylfolate 1000 mcg 100 vegetarian tablets

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Optimized Folate Benefits 

  • Supports both cardiovascular & cognitive health 
  • Helps maintain already-healthy homocysteine levels 
  • Delivers 1,000 mcg of the B vitamin folate 

Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with both cardiovascular and cognitive health. The B vitamin folate helps maintain already healthy homocysteine levels. The RDA for folate for adults is 400 mcg a day. Our formula provides 1,000 mcg of folate in the form of L-Methylfolate. 

Help maintain already healthy levels of the health biomarker homocysteine with 1,000 mcg of folate a day. 

 Folate, homocysteine & cardiovascular health 

Folate helps maintain healthy homocysteine levels already within the normal range. By helping to inhibit excess homocysteine, folate supports healthy levels of this important cardiovascular health biomarker.1 

5-MTHF, homocysteine & cognitive health 

Since people with elevated homocysteine levels have a greater risk of cognitive decline, getting enough folate is especially crucial for aging individuals attempting to maintain cognitive health.2,3 

Take alone or with B12 for enhanced effect 

The RDA for folate for non-pregnant or lactating adults is 400 mcg a day. This formula delvers 1,000 mcg of 5-MTHF folate. Supplement Facts 

Serving Size 1 vegetarian tablet 


Amount Per Serving 


Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt] 

1,000 mcg 

Other ingredients: microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid. 



Dosage and Use 

  • Take one (1) tablet daily with food, or as recommended by a healthcare practitioner. 



  • Do not purchase if outer seal is broken or damaged. 
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating. 

These statements have not been evaluated by the Food and Drug Administration. 

These products are not intended to diagnose, treat, cure, or prevent any disease